Item Type | Name |
Concept
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Proto-Oncogene Protein c-ets-1
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Concept
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Protein-Tyrosine Kinases
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Concept
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Protein Binding
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Concept
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Protein Transport
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Concept
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Protein Prenylation
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Concept
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Protein Processing, Post-Translational
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Concept
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Tumor Suppressor Protein p53
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Concept
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Mitogen-Activated Protein Kinases
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Concept
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Calcium-Calmodulin-Dependent Protein Kinases
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Concept
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p38 Mitogen-Activated Protein Kinases
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Concept
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Retinoblastoma Protein
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Concept
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Mitogen-Activated Protein Kinase Kinases
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 6
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Concept
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Oncogene Protein p21(ras)
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Concept
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Protein Kinase Inhibitors
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Concept
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Mitogen-Activated Protein Kinase 1
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Concept
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Sterol Regulatory Element Binding Protein 1
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Concept
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Ribosomal Protein S6 Kinases, 70-kDa
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Concept
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Protein Interaction Mapping
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Concept
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Receptors, G-Protein-Coupled
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Concept
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Protein Kinases
|
Concept
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Proto-Oncogene Protein c-ets-2
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Concept
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AMP-Activated Protein Kinases
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Concept
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GA-Binding Protein Transcription Factor
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Concept
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Mitogen-Activated Protein Kinase 3
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Concept
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ets-Domain Protein Elk-1
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Concept
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Protein-Arginine N-Methyltransferases
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Concept
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RNA-Binding Protein EWS
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Concept
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Protein Kinase C
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Concept
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BRCA1 Protein
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Concept
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RNA-Binding Protein FUS
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Concept
|
Protein Structure, Tertiary
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Concept
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Oncogene Protein v-akt
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Concept
|
rac1 GTP-Binding Protein
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Concept
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Receptor Protein-Tyrosine Kinases
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Concept
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Protein Stability
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Concept
|
Protein Tyrosine Phosphatases
|
Concept
|
Oncogene Protein gp140(v-fms)
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Concept
|
JNK Mitogen-Activated Protein Kinases
|
Concept
|
Focal Adhesion Protein-Tyrosine Kinases
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Concept
|
bcl-X Protein
|
Concept
|
Mitogen-Activated Protein Kinase 10
|
Concept
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Protein Isoforms
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Concept
|
cdc42 GTP-Binding Protein
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Concept
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Protein Engineering
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Concept
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Protein Array Analysis
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Academic Article
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Extra-embryonic function of Rb is essential for embryonic development and viability.
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Academic Article
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Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.
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Academic Article
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Pten in stromal fibroblasts suppresses mammary epithelial tumours.
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Academic Article
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Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis.
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Academic Article
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An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.
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Academic Article
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Allele-specific tumor spectrum in pten knockin mice.
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Academic Article
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Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
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Academic Article
|
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
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Academic Article
|
FGFR and PTEN signaling interact during lens development to regulate cell survival.
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Academic Article
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Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
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Academic Article
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Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
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Academic Article
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Ets-2 interacts with co-repressor BS69 to repress target gene expression.
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Academic Article
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RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment.
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Academic Article
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MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells.
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Academic Article
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Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B.
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Academic Article
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CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells.
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Academic Article
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The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene.
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Academic Article
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Inhibitor ?B kinase 2 is a myosin light chain kinase in vascular smooth muscle.
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Academic Article
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Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
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Academic Article
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Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
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Academic Article
|
Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors.
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Academic Article
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The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation.
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Academic Article
|
An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites.
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Academic Article
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Cyclic AMP-dependent activation of Rap1b.
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Academic Article
|
The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages.
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Academic Article
|
Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression.
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Academic Article
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Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse.
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Academic Article
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ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice.
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Academic Article
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Cry protein crystals: a novel platform for protein delivery.
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Academic Article
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The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).
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Academic Article
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TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.
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Academic Article
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The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor.
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Academic Article
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Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model.
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Academic Article
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The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor.
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Academic Article
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Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant.
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Academic Article
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Non-nuclear oncogenes and the regulation of gene expression in transformed cells.
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Academic Article
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Protein kinase C gamma expression mimics phorbol ester-induced transcriptional activation of a murine VL30 enhancer element.
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Academic Article
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Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
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Academic Article
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Analysis of the v-myb structural components important for transactivation of gene expression.
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Academic Article
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The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase.
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Academic Article
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Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo.
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Academic Article
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Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2.
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Academic Article
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Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling.
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Academic Article
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MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation.
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Academic Article
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ras oncogene activation of a VL30 transcriptional element is linked to transformation.
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Academic Article
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The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.
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Academic Article
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GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element.
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Academic Article
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Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis.
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Academic Article
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Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways.
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Academic Article
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Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
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Academic Article
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ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis.
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Academic Article
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Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein.
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Academic Article
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PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway.
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Academic Article
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Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.
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Academic Article
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MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation.
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Academic Article
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Transcription factor ets-2 plays an important role in the pathogenesis of pulmonary fibrosis.
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Academic Article
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A mouse model of yellow fluorescent protein (YFP) expression in hematopoietic cells to assess leukocyte-endothelial interactions in the microcirculation.
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Academic Article
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Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific Basal transcription initiation.
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Academic Article
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A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene.
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Academic Article
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A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer.
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Academic Article
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Activation of the ras-mitogen-activated protein kinase pathway and phosphorylation of ets-2 at position threonine 72 in human ovarian cancer cell lines.
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Academic Article
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CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
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Academic Article
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Control of interferon-tau gene expression by Ets-2.
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Academic Article
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Involvement of Ets, rel and Sp1-like proteins in lipopolysaccharide-mediated activation of the HIV-1 LTR in macrophages.
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Academic Article
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Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent.
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Academic Article
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Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.
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Academic Article
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Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling.
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Academic Article
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Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
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Academic Article
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Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.
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Academic Article
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SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility.
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Academic Article
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Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.
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Academic Article
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PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter.
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Academic Article
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Stromal PTEN determines mammary epithelial response to radiotherapy.
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Academic Article
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Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
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Academic Article
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Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
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Academic Article
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Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition.
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Academic Article
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Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
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Academic Article
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Hepatocyte-specific PKC? deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis.
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Academic Article
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Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia.
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Concept
|
Protein Kinase C beta
|
Concept
|
Forkhead Box Protein O1
|
Concept
|
Enhancer of Zeste Homolog 2 Protein
|
Concept
|
Src Homology 2 Domain-Containing, Transforming Protein 1
|
Concept
|
Zinc Finger Protein GLI1
|
Concept
|
Jagged-1 Protein
|
Concept
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S100 Calcium Binding Protein A7
|
Concept
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Zinc Finger Protein Gli2
|
Academic Article
|
PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
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Academic Article
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The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
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Academic Article
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Role of hepatic PKC? in nutritional regulation of hepatic glycogen synthesis.
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Academic Article
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Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
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